Since taking Daniel Jones with the sixth pick overall in the draft, the biggest question facing Pat Shurmur and the New York Giants is when does the kid replace Eli Manning at quarterback? A two-time Super Bowl MVP, the 38-year-old Manning is expected to start in the opening weekend of the season.
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| Detroit Lions vs Los Angeles Chargers | |
| Type: Point Spread - Status: OPEN | |
| Detroit Lions | -105 |
| Los Angeles Chargers | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |