Drew Brees answered any questions about how effective he would be coming back from thumb surgery, and the New Orleans Saints posted another convincing victory despite the absences of star running back Alvin Kamara and top receiving tight end Jared Cook. Now they have a bye to rest up before continuing
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| Detroit Lions vs Los Angeles Chargers | |
| Type: Point Spread - Status: OPEN | |
| Detroit Lions | -105 |
| Los Angeles Chargers | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
