The Bills had the fourth-worst Week One showing in the NFL since 1986, according to the stats at Football Outsiders. Jets RB Isaiah Crowell is averaging an NFL-high 10.2 yards per carry. Ryan Tannehill‘s 75-yard touchdown pass was tied for the longest of Week One. Sunday was Tom Brady‘s 119th game with
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| Detroit Lions vs Los Angeles Chargers | |
| Type: Point Spread - Status: OPEN | |
| Detroit Lions | -105 |
| Los Angeles Chargers | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
