Rookie RB Clyde Edwards-Helaire found the end zone for his first career NFL touchdown, and Patrick Mahomes has a pair himself as Kansas City is cruising in the opener.
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
