The New England Patriots lost Sony Michel to a knee injury, while Bills back LeSean McCoy suffered a head injury. Bilal Powell sustained a neck injury in the second quarter of the Jets’ loss to the Vikings on Sunday. Michel had to be helped off the field after he got twisted around by Bilal Nichols
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| Detroit Lions vs Los Angeles Chargers | |
| Type: Point Spread - Status: OPEN | |
| Detroit Lions | -105 |
| Los Angeles Chargers | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
