When the league suspended Tampa Bay Buccaneers quarterback Jameis Winston for the first three games of the season, people were quick to write-off the team considering how difficult their opening schedule was. The Bucs started off the year facing the New Orleans Saints, Philadelphia Eagles and Pittsburgh
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
