Injuries are piling up in the first halves of the early afternoon games, with Indianapolis Colts quarterback Jacoby Brissett leading the list. Brissett hurt his left knee, leaving the game at Pittsburgh early in the second quarter after one of his offensive linemen fell on his leg shortly after he released
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
