The crown jewel of Week 5 will be Sunday’s game at Arrowhead Stadium in Kansas City. In the best matchup on one side of the ball we’ve seen this season, the NFL’s stingiest scoring D (14.0 points per game) will try to slow down Patrick Mahomes and Andy Reid’s top-scoring unit (36.2).
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
