James Conner ran for 109 yards and the go-ahead touchdown midway through the fourth quarter as the Pittsburgh Steelers stayed perfect by rallying past the Houston Texans 28-21 on Sunday. Houston managed just 51 yards and two first downs after halftime as an early 11-point lead vanished. Houston started with the same mark in 2018 and rallied to win the AFC South.
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |