With Nick Mullens out with an elbow injury, Josh Johnson on the reserve/COVID-19 list, Jimmy Garoppolo still unavailable and C.J. Beathard the only healthy option who will start, San Francisco is signing Josh Rosen, sources say.
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |