Jimmy Garoppolo threw a 5-yard touchdown pass to Dante Pettis with 1:15 remaining and the San Francisco 49ers overcame five turnovers to beat the Pittsburgh Steelers 24-20 on Sunday for their first 3-0 start in 21 years. The Niners gave the ball away four times in the first half and then lost a fumble
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |