The New York Giants didn’t have much of the running game with Saquon Barkley out of the lineup with an ankle injury, and things haven’t gotten much better since the 2018 NFL Offensive Rookie of the Year returned to the lineup three weeks ago. With the exception of a career-high 65-yard reception
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| Detroit Lions vs Los Angeles Chargers | |
| Type: Point Spread - Status: OPEN | |
| Detroit Lions | -105 |
| Los Angeles Chargers | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |