Coach: Kyle Shanahan (second year — 8-20). Record: 2-10 (fourth in NFC West). Last week: Lost 43-16 at Seattle. Next week: vs. Seattle. PLAYERS TO WATCH 1. TE George Kittle Statistics: A 2016 fifth-round pick from Iowa, Kittle is one of the 49ers’ few bright spots. He leads the team in catches (62
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| Detroit Lions vs Los Angeles Chargers | |
| Type: Point Spread - Status: OPEN | |
| Detroit Lions | -105 |
| Los Angeles Chargers | -115 |
| Philadelphia Eagles vs Dallas Cowboys | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -110 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |