The Rams head into their Week 12 contest against the 49ers with the trio of Jared Goff, Robert Woods and Cooper Kupp spearheading a strong passing attack.
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
