Dak Prescott had the second perfect passer rating in the history of the Dallas Cowboys in his first game with new offensive coordinator Kellen Moore. The defending NFC East champions couldn’t have asked for much more from a no-doubt 35-17 win over the New York Giants in the opener, particularly
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| Detroit Lions vs Los Angeles Chargers | |
| Type: Point Spread - Status: OPEN | |
| Detroit Lions | -105 |
| Los Angeles Chargers | -115 |
| Philadelphia Eagles vs Dallas Cowboys | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -110 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
