Eli Manning, Philip Rivers and Ben Roethlisberger have always shared a link by virtue of when and where they were drafted. All three quarterbacks came into the NFL in 2004 and Manning was selected by the Chargers with the first overall pick. He was quickly traded to the Giants for a package that included
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| Detroit Lions vs Los Angeles Chargers | |
| Type: Point Spread - Status: OPEN | |
| Detroit Lions | -105 |
| Los Angeles Chargers | -115 |
| Philadelphia Eagles vs Dallas Cowboys | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -110 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
