Five teams are in position to clinch playoff berths in Week 15 of the NFL schedule. In the AFC, where Baltimore has won the North and Kansas City has taken the West, both New England and Buffalo can get in from the East. The Patriots do so with a win or tie at lowly Cincinnati.
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| Detroit Lions vs Los Angeles Chargers | |
| Type: Point Spread - Status: OPEN | |
| Detroit Lions | -105 |
| Los Angeles Chargers | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
