Oklahoma won another Big 12 title and made it to the College Football Playoff again in its first season without coach Bob Stoops on the sideline. The Sooners, who have won the past three Big 12 titles with quarterback Baker Mayfield, will now be trying to do it again without the Heisman Trophy winner
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |