At the quarter-pole of the NFL season, no one has been able to slow Patrick Mahomes and the high-flying Kansas City Chiefs. One of two undefeated teams in the NFL, the Chiefs (4-0) will try to remain perfect when they host the Jacksonville Jaguars (3-1) on Sunday in what shapes up as a classic matchup
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
