Although Alex Smith probably will miss more than one game after separating his right shoulder, the San Francisco quarterback is sticking with the best-case scenario until he hears something worse. Smith definitely won’t play in the 49ers’ next game against Baltimore after getting hurt on the third play of their 23-3 loss to Seattle on Sunday.
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| Detroit Lions vs Los Angeles Chargers | |
| Type: Point Spread - Status: OPEN | |
| Detroit Lions | -105 |
| Los Angeles Chargers | -115 |
| Philadelphia Eagles vs Dallas Cowboys | |
| Type: Total - Status: OPEN | |
| Under | -105 |
| Over | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
