Departing from its usual custom of allowing the Super Bowl champions to host the opening game of the next season, the NFL said its 100th season will open with the league’s oldest rivalry, between the Chicago Bears and Green Bay Packers. NBC will host the contest on Thursday, September 5, under a
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| Detroit Lions vs Los Angeles Chargers | |
| Type: Point Spread - Status: OPEN | |
| Detroit Lions | -105 |
| Los Angeles Chargers | -115 |
| Philadelphia Eagles vs Dallas Cowboys | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -110 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
