The latest Week 11 NFL odds indicate that scoreboards will light up at a historic rate on Sunday and Monday. Five games have an Over-Under of more than 49 points, including eye-popping NFL totals like 56 for Eagles vs. Saints and 63 for Chiefs vs. Rams, one of the highest Vegas has ever seen. However
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| Detroit Lions vs Los Angeles Chargers | |
| Type: Point Spread - Status: OPEN | |
| Detroit Lions | -105 |
| Los Angeles Chargers | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
