The Steelers and Panthers put up a combined 73 points on Thursday night, and the latest Week 10 NFL odds indicate there could be even more high-scoring games on the way. There are also plenty of large NFL lines this week, signaling possible mismatches up and down the Week 10 NFL schedule. Five remaining
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| Detroit Lions vs Los Angeles Chargers | |
| Type: Point Spread - Status: OPEN | |
| Detroit Lions | -105 |
| Los Angeles Chargers | -115 |
| Philadelphia Eagles vs Dallas Cowboys | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -110 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
