A catfight between two 3-1 teams — the Panthers and Lions — in the wake of the flap over Cam Newton  sexist remarks and a battle between the winless Chargers and New York Giants are among the early storylines in Week 5. To keep tabs on some of the choicest highlights and other big news throughout Sunday
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| Detroit Lions vs Los Angeles Chargers | |
| Type: Point Spread - Status: OPEN | |
| Detroit Lions | -105 |
| Los Angeles Chargers | -115 |
| Philadelphia Eagles vs Dallas Cowboys | |
| Type: Total - Status: OPEN | |
| Under | -110 |
| Over | -110 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |