A catfight between two 3-1 teams — the Panthers and Lions — in the wake of the flap over Cam Newton  sexist remarks and a battle between the winless Chargers and New York Giants are among the early storylines in Week 5. To keep tabs on some of the choicest highlights and other big news throughout Sunday
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
