Drew Brees holds the edge in the quarterback rivalry with Cam Newton, winning eight of 14 head-to-head matchups straight up, including the last three in a row. And Brees’ New Orleans Saints are 9-5 against the spread over that span against Carolina. Brees and Newton face off for the 15th time on
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |