Kyler Murray remains the betting favorite to be selected by the Arizona Cardinals with the No. 1 overall pick in the NFL draft, followed by Nick Bosa and Quinnen Williams.
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
