Patrick Mahomes and Lamar Jackson put on a show, living up to the big hype entering the game, but it was the reigning MVP who led his team to a Week 3 win.
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |