The Buccaneers were better than the Saints last year. The Bengals were better than the Colts. The Panthers were better than the Cowboys. The Packers were better than the Bears. And the Broncos were better than the Seahawks. At least, they were in Week One. Those were five Week One matchups from the 2018
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |