49ers QB Jimmy Garoppolo has a chance to play Sunday against the Giants despite his high ankle sprain, while RB Tevin Coleman is expected to miss multiple weeks with a knee injury.
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |