Former Clemson QB Trevor Lawrence was the top pick in the NFL draft, ushering in a new era in Jacksonville. The Jags later selected Lawrence’s former teammate, RB Travis Etienne, with the 25th overall pick.
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |