The first full week of 2019 preseason games have been played, and the 16 Week One contests included 16 replay reviews of calls and non-calls of offensive and defensive pass interference. Based on a review of the official NFL game books for the games played on Thursday, Friday, and Saturday nights, 14
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |