Since Week 8, Garoppolo has a QBR of 64.4 (fourth in the NFL), 1,831 passing yards (third), 11 touchdowns (tied for 8th) and the 49ers are 5-2.
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |