Mayfield, the No. 1 pick of the 2018 draft, has shown leadership this season, while going from potential NFL star with the Browns to backup with the Panthers.
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |