Jared Goff and Carson Wentz are an NFL rarity. Wentz finished third in NFL MVP voting his sophomore season when the Eagles won their first Super Bowl title, doing it without him after he tore two knee ligaments in his only other meeting against Goff and the Rams. Goff led Los Angeles to a Super Bowl appearance the following season but lost 13-3 to New England.
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
