It was the first time in a long time that No. 10 wasn't on the sidelines for the Giants during the 2020 season. But Eli Manning might be back with the team in some capacity after just one season off.
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
