Two wins in three games earned Bills rookie quarterback Trent Edwards the starting job, and sent J.P. Losman to a familiar place — the bench. Coach Dick Jauron made the announcement on Tuesday in a two-paragraph statement issued by the team as the Bills (2-4) prepare to travel to play the New York Jets on Sunday.
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |