Panthers wide receiver Curtis Samuel injured his left ankle early in the third quarter, requiring help from trainers to hobble to the locker room. The team lists him as questionable to return. The Panthers also lost center, Tyler Larsen, who is questionable to return with a foot injury. Starting center
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| Detroit Lions vs Los Angeles Chargers | |
| Type: Point Spread - Status: OPEN | |
| Detroit Lions | -105 |
| Los Angeles Chargers | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
