Patrick Mahomes and Lamar Jackson are two of the NFL’s most dynamic young players. Mahomes and the Kansas City Chiefs are the defending Super Bowl champs and Jackson and the Baltimore Ravens, who finished with the top regular-season record last season, hope to get past them and reach the Super Bowl this season. Both teams are off to 2-0 starts this season and kept the top two spots in this week’s AP Pro32 poll.
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
