The NFL has moved the Week 5 game between the Broncos and Patriots to Monday night. The move comes after the Patriots played a Monday night game in Week 4 at the Chiefs after starting quarterback Cam Newton tested positive for COVID-19. New England is working its way through the COVID situation, as they had zero positive COVID tests on Thursday, and had to go virtual Wednesday and couldn't practice on-field. Reports indicate the Broncos-Patriots game at Gillette Stadium will be at 3:05 p.m. MT
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
