Peyton Manning grew up in New Orleans, the favorite son in a city where his father, Archie, was considered royalty. Drew Brees grew up in Texas, an overlooked high school recruit who eventually resurrected Purdue’s image as Quarterback U. Now the New Orleans native and the Purdue favorite have changed places.
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
