Big winners at the NFL Honors included Bills QB Josh Allen (MVP), Eagles RB Saquon Barkley (top offensive player), Commanders QB Jayden Daniels (top offensive rookie) and Broncos CB Patrick Surtain II (top defensive player).
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| Detroit Lions vs Los Angeles Chargers | |
| Type: Point Spread - Status: OPEN | |
| Detroit Lions | -105 |
| Los Angeles Chargers | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
