The Bills, who closed as consensus 17-point underdogs to the previously unbeaten Vikings, on Sunday pulled off the biggest NFL upset in 23 years, routing Minnesota 27-6.
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
