Two NFC East quarterbacks were dominant in Week 6, but Eli Manning managed just a 3.6 Total QBR. Here are the week’s best and worst performances.
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
