The Rams and 49ers are hoping Todd Gurley and Jimmy Garoppolo can recover from injury, while the Seahawks hope for more of the same from Russell Wilson.
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
