The 49ers on Wednesday removed Arik Armstead and Hroniss Grasu from the COVID-19 list, leaving 7 players on the list for San Francisco.
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
