Led by Jimmy Garoppolo, the 49ers scratched and clawed their way back from a 17-point deficit for a dramatic overtime victory against the rival Rams to clinch their ticket to the postseason.
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
