Jimmy Garoppolo finished 11-of-19 for 131 yards with a touchdown and an interception for a passer rating of 74.7 in his first playoff start. The 49ers will face the winner of the Seahawks-Packers game next.
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |