The competitive balance in NFL 2018 is such that it would be no surprise if any – or all – of the visitors win on wild-card weekend to begin the 2019 calendar. Hey, the largest spread is a mere 6 1-2 points, Bears over Eagles.
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| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| NFC Conference | -105 |
| AFC Conference | -115 |
| AFC Conference vs NFC Conference | |
| Type: Moneyline - Status: OPEN | |
| AFC Conference | -115 |
| NFC Conference | -105 |
