Mike Yastrzemski, the grandson of Hall of Famer Carl Yastrzemski who was drafted in 2013, started in left field and went 0-for-3 for the Giants in his major league debut.
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| Atlanta Braves vs Minnesota Twins | |
| Type: Total - Status: OPEN | |
| Over - 1I | +240 |
| Under - 1I | -340 |
| Boston Red Sox vs Chicago White Sox | |
| Type: Runline - Status: OPEN | |
| Chicago White Sox - 1H | +100 |
| Boston Red Sox - 1H | -130 |
| Baltimore Orioles vs Cincinnati Reds | |
| Type: Moneyline - Status: OPEN | |
| Baltimore Orioles | -202 |
| Cincinnati Reds | +166 |
| Pittsburgh Pirates vs Cleveland Guardians | |
| Type: Moneyline - Status: OPEN | |
| Pittsburgh Pirates - 1H | -130 |
| Cleveland Guardians - 1H | +100 |
| Philadelphia Phillies vs Miami Marlins | |
| Type: Moneyline - Status: OPEN | |
| Miami Marlins | +265 |
| Philadelphia Phillies | -335 |
| Toronto Blue Jays vs Seattle Mariners | |
| Type: Moneyline - Status: OPEN | |
| Seattle Mariners | -120 |
| Toronto Blue Jays | +100 |
| Detroit Tigers vs Kansas City Royals | |
| Type: Total - Status: OPEN | |
| Under - 1I | -450 |
| Over - 1I | +300 |
| New York Mets vs St. Louis Cardinals | |
| Type: Total - Status: OPEN | |
| Under - 1I | -420 |
| Over - 1I | +285 |
| Tampa Bay Rays vs New York Yankees | |
| Type: Moneyline - Status: OPEN | |
| Tampa Bay Rays | +138 |
| New York Yankees | -164 |
| Milwaukee Brewers vs Athletics | |
| Type: Total - Status: OPEN | |
| Over - 1I | +240 |
| Under - 1I | -340 |
| Chicago Cubs vs Arizona Diamondbacks | |
| Type: Moneyline - Status: OPEN | |
| Arizona Diamondbacks - 1H | +110 |
| Chicago Cubs - 1H | -145 |
| Texas Rangers vs Los Angeles Dodgers | |
| Type: Total - Status: OPEN | |
| Over - 1H | -120 |
| Under - 1H | -110 |
| Colorado Rockies vs Washington Nationals | |
| Type: Runline - Status: OPEN | |
| Colorado Rockies | -160 |
| Washington Nationals | +135 |
| Los Angeles Angels vs San Francisco Giants | |
| Type: Moneyline - Status: OPEN | |
| San Francisco Giants | -113 |
| Los Angeles Angels | -107 |
| Houston Astros vs San Diego Padres | |
| Type: Total - Status: OPEN | |
| Over - 1H | -130 |
| Under - 1H | +100 |
| Colorado Rockies vs Washington Nationals | |
| Type: Total - Status: OPEN | |
| Under - 1I | -215 |
| Over - 1I | +160 |
