The New York Yankees would host a tiebreaker playoff if one is needed to decide the AL wild-card race. The Yankees won coin flips with both Detroit and Seattle conducted Friday by the commissioner’s office. Detroit would host Seattle. Philadelphia would host the New York Mets in an NL East tiebreaker. In the NL Central, the Chicago Cubs would host Milwaukee, St.
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| Cleveland Guardians vs Milwaukee Brewers | |
| Type: Runline - Status: OPEN | |
| Cleveland Guardians - 1H | -125 |
| Milwaukee Brewers - 1H | -105 |
| Detroit Tigers vs Boston Red Sox | |
| Type: Runline - Status: SUSPENDED | |
| Boston Red Sox - 1I | |
| Detroit Tigers - 1I | |
| Philadelphia Phillies vs St. Louis Cardinals | |
| Type: Moneyline - Status: OPEN | |
| St. Louis Cardinals - 1I | +120 |
| Philadelphia Phillies - 1I | -160 |
| New York Mets vs Pittsburgh Pirates | |
| Type: Runline - Status: OPEN | |
| New York Mets | +155 |
| Pittsburgh Pirates | -180 |
| Atlanta Braves vs Washington Nationals | |
| Type: Runline - Status: OPEN | |
| Atlanta Braves | +120 |
| Washington Nationals | -140 |
| Chicago Cubs vs Miami Marlins | |
| Type: Total - Status: OPEN | |
| Over | -110 |
| Under | -110 |
| Texas Rangers vs Colorado Rockies | |
| Type: Total - Status: OPEN | |
| Over - 1H | -105 |
| Under - 1H | -125 |
| Houston Astros vs Kansas City Royals | |
| Type: Total - Status: OPEN | |
| Under | -120 |
| Over | +100 |
| San Diego Padres vs Los Angeles Angels | |
| Type: Runline - Status: OPEN | |
| San Diego Padres - 1H | +100 |
| Los Angeles Angels - 1H | -130 |
| Seattle Mariners vs New York Yankees | |
| Type: Moneyline - Status: OPEN | |
| Seattle Mariners - 1H | +105 |
| New York Yankees - 1H | -135 |
| San Francisco Giants vs Arizona Diamondbacks | |
| Type: Runline - Status: OPEN | |
| Arizona Diamondbacks | -220 |
| San Francisco Giants | +180 |